Uric acid (urate)

Uric acid (urate) is the chemical that causes gout. It forms crystals in joints, causing a very painful arthritis. Uric acid is also involved in some uncommon inherited kidney diseases. It may be important in more common kidney diseases and in high blood pressure, but in general, moderately high uric acid isn't thought to need treatment unless you have gout. Normal = 180-480 micromol/l (3-7 mg/dl). It is slightly higher in men.

Result
Comments
below 180
Low values are seen in some rare diseases and after treatment with drugs that lower uric acid
180-480
Normal
You can sometimes get gout with normal levels but it is uncommon
480-650
Levels are raised in those with kidney disease, but high levels also common in the general population. Usually no treatment unless you have gout.
900+
Very high - can cause acute kidney failure or be a sign of a serious inherited disease.

Uric acid levels fall during normal pregnancy.

During treatment with allopurinol, it is common to aim for a serum uric acid level of less than 300 to prevent attacks of gout.

More info about urate from Lab Tests Online

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This page created 11th March 2009, last modified Sun, Jul 18, 2010, on the Renal PatientView website